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ATP-sensitive [K.sup.+] channel-dependent regulation of glucagon release and electrical activity by glucose in wild-type and SUR[1.sup.-/-] mouse [alpha]-cells
Patch-clamp recordings and glucagon release measurements were combined to determine the role of plasma membrane ATP-sensitive [K.sup.+] channels ([K.sub.ATP] ......(Continue Reading) Peroxisome proliferator-activated receptor [alpha] and [gamma] agonists directly bind and close [K.sub.ATP] channel - PPAR - Islet Biology—Channels,
We have already demonstrated that both troglitazone and pioglitazone, peroxisome proliferator-activated receptor (PPAR) [gamma] ligands, stimulate acute-phase ......(Continue Reading)Assembly of Plant Shaker-Like K^sub out^ Channels Requires Two Distinct Sites of the Channel [alpha]-Subunit
ABSTRACT SKOR and GORK are outward-rectifying plant potassium channels from Arabidopsis thaliana. They belong to the Shaker superfamily of voltage-dependent ......(Continue Reading)Effect of Nanomolar Concentrations of Sodium Dodecyl Sulfate, a Catalytic Inductor of [alpha]-Helices, on Human Calcitonin Incorporation and Channel Formation
ABSTRACT Human Calcitonin (hCt) is a peptide hormone which has a regulatory action in calcium-phosphorus metabolism. It is currently used as a therapeutic ......(Continue Reading)Conformational Changes in Alamethicin Associated with Substitution of Its [alpha]-Methylalanines with Leucines: A FTIR Spectroscopic Analysis and Correlation
ABSTRACT Alamethicin, a 20 residue-long peptaibol remains a favorite high voltage-dependent channel-forming peptide. However, the structural significance ......(Continue Reading)
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