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Hyperglycemia induces monocytic release of interleukin-6 via induction of protein kinase C-[alpha] and-[beta] Diabetes confers an increased propensity to atherosclerosis. Inflammation is pivotal in atherogenesis, and diabetes is a proinflammatory state. Interleukin ......(Continue Reading) Nutritional status and muscle strength in patients with emphysema and severe [[alpha].sub.1]-antitrypsin deficiency - clinical investigations Background: The association between emphysema and weight loss is well known. Severe [[alpha].sub.1]-antitrypsin deficiency is an important risk factor ......(Continue Reading)Biochemical efficacy and safety of a new pooled human plasma [[alpha].sub.1]-antitrypsin, respitin Background: Augmentation therapy with pooled human plasma-derived [[alpha].sub.1]-antitrypsin (AAT) has been shown to have biochemical efficacy in restoring ......(Continue Reading)Production of soluble tumor necrosis factor receptors and tumor necrosis factor-[alpha] by alveolar macrophages in sarcoidosis and extrinsic allergic alveolitis Background: Alveolar macrophage (AM)-derived tumor necrosis factor (TNF)-[alpha] plays a pivotal role in the pathogenesis of sarcoidosis and extrinsic ......(Continue Reading)Elevated production of tumor necrosis factor-[alpha] by monocytes in patients with obstructive sleep apnea syndrome Study objectives: Tumor necrosis factor (TNF)-[alpha] is involved in the pathogenesis of atherosclerosis. In the present study, we examined TNF-[alpha] ......(Continue Reading)
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